| Ion Channel expression, function and modulation | |
![]() Dr Rod Rietze Post Doctoral Fellows
Daniel Blackmore, PhD Research Assistants
Preethi Eldi Beatrice Large PhD Students Kristin Hatherley, BA, BSc (Hons) |
Dr Rodney L. RietzeHead, Neural Stem Cells and Aging LaboratoryPfizer Australia Senior Research Fellow Tel: (+61-7) 33466351 Fax: (+61 7) 3346 6051 The focus of our lab is to understand how the activity of endogenous mammalian neural stem cells is regulated, so as to harness their regenerative capacity and ultimately prevent or restore cognitive function lost due to aging or disease. Overall, our research is focus on four main areas: 1. The development of novel assays to discriminate bona fide neural stem cells from more differentiated progeny in vitro and in vivo ... [more] 2. The phenotypic characterisation of endogenous and cultured adult neural stem cells and their progeny ... [more] 3. Discerning the regulatory effects of growth hormone signaling on endogenous stem cells ... [more] 4. Characterisation and prevention of age-related alterations in endogenous neural stem cell prevalence and function ... [more] Rietze, R. L., Valcanis, H., Brooker, G.F., Thomas, T., Voss, A.K. and Bartlett, P.F. (2001) Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 412: 736-739.Turnley, A.M., Faux, C.H., Rietze, R.L., Coonan, J.R., and Bartlett, P.F. (2002) Suppressor of cytokine signaling-2 (SOCS2) regulates neuron production by inhibiting Growth Hormone signaling. Nature Neuroscience 5: 211-218. Reynolds, BA and Rietze, R.L. (2005) Neural stem cells and neurospheres – re-evaluating the relationship. Nature Methods 2(5) 333-335. Golmohammadi, M.G., Blackmore, D.G., Large, B., Azari, H., Esfandiary, E, Paxinos, G., Franklin, K.B.J., Reynolds, B.A., and Rietze, R.L. (2008) Comparative analysis of the frequency and distribution of stem and progenitor cells in the adult mouse brain. Stem Cells 26(4) 979-987. Louis, S.A., Rietze, R.L., Delerolle, L., Wagey, R., Thomas, T., Eaves, A., Reynolds, B.A. (2008) Enumeration of neural stem and progenitor cells in the neural colony forming cell assay. Stem Cells 26(4) 988-996. |

