Mr Hugh Simpson, of the Computational Neuroscience unit within the Queensland Brain Institute, will speak on the subject of 'computational modelling of retinotectal map development' on Wednesday 13 April 2011.

Topographic maps are connection patterns found repeatedly in the brain, and are often associated with areas of sensory processing, such as vision and hearing. The study of the development of these maps provides a highly informative model system for exploring how the brain wires itself up. We present computational and mathematical modelling of the development of one example of these maps, the retinotectal map. We have developed a computational model of map formation that unifies previously disparate experimental findings, and sheds light on how particular mechanisms operate in map development. We present calculations based on physical limits arguments to demonstrate some of the limits on map precision, and how these might affect map structure and function. Preliminary results from in vivo imaging of map development in zebrafish are also presented.

Date: 13 April 2011
Time: 12-1pm
Location: Level 7 Auditorium, QBI Building (#79), St Lucia Campus

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