The QBI Advanced Microimaging and Analysis Facility is built around 24 high-end instruments. These include specialised microscope systems capable of super-resolution imaging, automated imaging, optical sectioning, tiled imaging of large areas and neuronal morphology analysis. Five confocal systems allow high-resolution imaging (Zeiss LSM710 and LSM510 METAs), high-speed live imaging (3i Yokogawa W1 SDC) and immersion microscopy (LSM PASCAL). Super-resolution imaging techniques, including Structured Illumination Microscopy (SIM) and single molecule imaging techniques (STORM/PALM), are made possible on a Zeiss ELYRA PS and Roper Ilas2 instrument. Stereology, slide-scanning, calcium imaging, TIRF, FLIM, FRET, FRAP, 2-photon imaging and a variety of other imaging techniques are also possible within the facility.
In addition to state-of-the-art instrumentation, a dedicated team of experienced staff provide training, support and experimental advice to researchers. This combination provides QBI researchers and collaborators with the tools to undertake diverse studies, from tissue mapping and 3-D reconstruction of neuronal populations through to rapid imaging of neural activity and intracellular trafficking.