Dr Martin Sale

Contact Information

m.sale@uq.edu.au
Building: QBI Building #79
Room: 3-3-1
Tel: +61 7 334 66326

Mailing Address

Queensland Brain Institute
The University of Queensland
Brisbane, 4072
Queensland,
Australia

Short biography

Research directions

Selected publications

 

Short biography

Martin Sale completed a Bachelor of Science (First Class Honours) at the University of Adelaide in 1996. His Honours project investigated motor cortex excitability in Parkinson's Disease patients. He was awarded the Physiology prize as the top honours student in his year. Following this, he completed a Physiotherapy Degree in 2000 and spent time working in neurological physiotherapy departments around Australia. He returned to research in 2004, and worked with Dr John Semmler at Deakin University, Melbourne, Australia. This research focussed on three areas a) Motor unit coherence and habitual physical activity, b) Motor unit activity and neuromuscular fatigue, and c) Cortical control of fine motor skills with ageing and strength training. In 2005 he commenced a PhD (NH&MRC Dora Lush Biomedical Scholarship) at the University of Adelaide, investigating the neural mechanisms involved in cortical plasticity, in particular how time of day influences cortical plasticity. He subsequently became expert in the use of transcranial magnetic stimulation (TMS) to non-invasively stimulate human cortex. Following completion of his PhD in 2009 he commenced a post-doctoral position at The University of Queensland in the cognitive neuroscience lab of Professor Jason Mattingley. He received a NHMRC postdoctoral fellowship in 2011 to investigate the neural adaptations associated with prism adaptation in patients with hemispatial neglect. He is gaining expertise in functional brain imaging (fMRI, resting-state MRI, DTI) and is looking to combine these imaging approaches with TMS to probe the neural mechanisms associated with plasticity.
 

Research directions

  • Factors influencing the induction of plasticity in human cortex
  • The interaction between mirror neurons and neuroplasticity
  • Spatial neglect and prism adaptation
  • Neural adaptations to training

Selected publications

Brouwer B, Sale MV, Nordstrom MA (2001). Asymmetry of motor cortex excitability during a simple motor task: relationships with handedness and manual performance. Experimental Brain Research 138:467-476 (IF: 2.118)

Semmler JG, Sale MV, Meyer FG, Nordstrom MA (2004). Motor-unit coherence and its relation with synchrony are influenced by training. Journal of Neurophysiology 92:3320-3331 (IF: 3.853)

Sale MV, Semmler JG (2005). Age-related differences in corticospinal control during functional isometric contractions in left and right hands. Journal of Applied Physiology 99:1483-1493 (IF: 3.037)

Kidgell DJ, Sale MV, Semmler JG (2006). Motor unit synchronization measured by cross-correlation is not increased by short-term strength training of a hand muscle. Experimental Brain Research 175:745-753 (IF: 2.118)

Sale MV, Ridding MC, Nordstrom MA (2007) Factors influencing the magnitude and reproducibility of corticomotor excitability changes induced by paired associative stimulation. Experimental Brain Research 181:615-626 (IF: 2.118)

Sale MV, Ridding MC, Nordstrom MA (2008). Cortisol inhibits neuroplasticity induction in human motor cortex. Journal of Neuroscience 28:8285-8293 (IF: 7.490)

Sale MV, Nordstrom MA, Brophy BP, Thompson PD (2010). Pallidotomy does not ameliorate abnormal intracortical inhibition in Parkinson’s disease. Journal of Clinical Neuroscience 17:711-716 (IF 1.247)

Sale MV, Ridding MC, Nordstrom MA (2010). Circadian modulation of neuroplasticity in humans, and potential therapeutic implications. Reviews in the Neurosciences 21:55-66 (IF 2.413)

Smith AE, Sale MV, Higgins RD, Wittert G, Pitcher JB (2011). Male human motor cortex stimulus-response characteristics are not altered by ageing. Journal of Applied Physiology 110:206-212 (IF 3.753)

Molenberghs P, Sale MV (2011) Testing for spatial neglect with line bisection and target cancellation: are both tasks really unrelated?. PLoS ONE 6(7): e23017 (IF 4.092)

Molenberghs P, Sale MV, Mattingley JB (2012) Is there a critical lesion site for unilateral spatial neglect? A meta-analysis using activation likelihood estimation. Frontiers in Human Neuroscience (IF 2.339)

Kamke MR, Hall MG, Lye H, Sale MV, Fenlon L, Carroll T, Riek S, Mattingley JB (2012) Visual attentional load influences plasticity in the human motor cortex. Journal of Neuroscience 32:7001-7008 (IF 7.115)

Sale MV, Mattingley JB (2012) Selective enhancement of motor cortical plasticity by observed mirror-matched actions. Submitted to NeuroImage (IF 5.895)

Sale MV, Ridding MC, Nordstrom MA (2012) Time of day does not modulate improvements in motor performance following a repetitive ballistic motor training task. Submitted to Neural Plasticity (IF 2.000)

Amarasena J, Sale MV, Nordstrom MA (2012) Language tasks increase hand motor cortex excitability without altering intracortical inhibition. Submitted to Clinical Neurophysiology

Conference abstracts

Sale MV, Nordstrom MA, Thompson PD (1996) Motor cortex excitability in Parkinson's disease. Proceedings of the Australian Neuroscience Society 7:50

Sale MV, Nordstrom MA, Thompson PD (1997) Motor cortex excitability is unaltered following pallidotomy in patients with Parkinson's disease. Proceedings of the Australian Physiological and Pharmacological Society 28, 95P

Brouwer B, Nordstrom MA, Sale MV (1998) Association of corticospinal excitability during task performance with handedness and dexterity. In: Peripheral and Spinal Mechanisms in the Neural Control of Movement, pp.60

Brouwer B, Nordstrom MA, Sale MV (1998) Association of corticospinal excitability during task performance with handedness and dexterity. Society for Neuroscience Abstracts 24:1414

Semmler JG, Sale MV, Meyer FG, Nordstrom MA (2004) Motor unit coherence is influenced by skilled hand muscle use in humans. Proceedings of the XVth Congress of the International Society of Electrophysiology and Kinesiology, Boston USA, June 18-21, 2004, ISBN 0-87270-136-0, pp.154

Sale MV, Kidgell DJ, Semmler JG (2005) Task-dependent changes in motor cortex excitability in a hand muscle of young and old adults. Proceedings of the Australian Neuroscience Society 16:48

Sale MV, Ridding MC, Nordstrom MA (2006) Variability of two paired associative stimulation (PAS) protocols used to induce neuroplastic changes in human motor cortex. Proceedings of the Australasian Winter Conference on Brain Research 24:10.5

Semmler JG, Sale MV, Kidgell DJ (2006) Motor unit synchronization measured by cross-correlation is not increased with strength training of a hand muscle. Proceedings of the Australasian Winter Conference on Brain Research 24:2.4

Sale MV, Brierley JC, Forbes E, Kreuger E, Oduor YY, Rogasch NC, Tan KP, Nordstrom MA (2007) Synchronous fluctuations in corticomotor excitability are enhanced for functionally related pairs of intrinsic hand muscles. IBRO International World Congress of Neuroscience, Melbourne Australia July 12-17, POS-SAT-264

Lavender AP, Sale MV, Semmler JG, Nordstrom MA (2007) Reduced corticomotor excitability in older adults. IBRO World Congress of Neuroscience Satellite Meeting "Motor Control at the Top End", Darwin Australia July 18-21, pp.82

Sale MV, Ridding MC, Nordstrom MA (2007) Circadian modulation of associative plasticity and intracortical inhibition in human motor cortex. Program no 82.4 2007 Abstract Viewer/Itinerary Planner. Washington DC. Society for Neuroscience 2007. Online

Sale MV, Ridding MC, Nordstrom MA (2008) Cortisol inhibits neuroplasticity induction in human motor cortex. Australian Society for Medical Research annual meeting 2008 (SA), pp.26

Amarasena J, Sale MV, Gan C, Honey D, Lai J, Meredith I-R, Nordstrom MA (2009) Language tasks increase hand motor cortex excitability without altering intracortical inhibition. Proceedings of the Australian Neuroscience Society 20:POS-THU-168

Taylor A,Cocchi L, Sale MV, Zalesky A, Hearne L, Mattingley JB (2012) The effects of TMS of motor cortex on large-scale functional brain networks. 3rd Brain Plasticity Symposium Circuits, Synapses and Behaviour. 14 - 16 September 2012, Brisbane.

Hearne L, Cocchi L, Sale MV, Zalesky A, Taylor A, Mattingley JB (2012) The effects of TMS of motor cortex on large-scale functional brain networks. 3rd Brain Plasticity Symposium Circuits, Synapses and Behaviour. 14 - 16 September 2012, Brisbane.

Sale MV, Mattingley JB (2012) Motor cortical plasticity is enhanced by passive observation of mirror-matched limb movements. Poster no 904 2012 Abstract Viewer/Itinerary Planner. New Orleans. Society for Neuroscience 2012. Online

Molenberghs P, Sale MV, Mattingley J (2012) Is there a critical lesion site for unilateral spatial neglect? A meta-analysis using activation likelihood estimation. Poster no 594 2012 Abstract Viewer/Itinerary Planner. New Orleans. Society for Neuroscience 2012. Online

Sale MV, Mattingley JB (2012) Motor cortical plasticity is enhanced by passive observation of mirror-matched limb movements. Australian Cognitive Neuroscience Society conference. Brisbane.

Kamke MR, Ryan A, Sale MV, Riek S, Carroll TJ, Mattingley JB (2012) Visual spatial attention influences plasticity in the human motor cortex. Australian Cognitive Neuroscience Society conference. Brisbane.

Hearne L, Cocchi L, Sale MV, Zalesky A, Taylor A, Mattingley JB (2012) Dissociable effects of focal inhibition and excitation of primary motor cortex on functional connectivity within the motor network. Australian Cognitive Neuroscience Society conference. Brisbane.

Taylor AL, Cocchi L, Sale MV, Hearne L, Mattingley JB (2012) Focal disruption to primary motor cortex causes widespread changes in functional connectivity. Australian Cognitive Neuroscience Society conference. Brisbane.

Dickins DS, Sale MV, Mattingley JB, Kamke MR (2012) The effect of visual spatial attention on bilateral plasticity in the human motor cortices. Australian Cognitive Neuroscience Society conference. Brisbane.