Professor Geoffrey Goodhill - Computational Neuroscience
Professor Goodhill did a Joint Honours BSc in Mathematics and Physics at Bristol University (UK), followed by an MSc in Artificial Intelligence at Edinburgh University and a PhD in Cognitive Science at Sussex University. Following a postdoc at Edinburgh University he moved to the USA in 1994, where he did further postdoctoral study in Computational Neuroscience at Baylor College of Medicine and the Salk Institute. Professor Goodhill formed his own lab at Georgetown University in 1996, where he was awarded tenure in the Department of Neuroscience in 2001. In 2005 he moved to a joint appointment between the Queensland Brain Institute and the School of Mathematical and Physical Sciences at the University of Queensland.
From 2005-2011 Professor Goodhill was Editor-in-Chief of the journal "Network: Computation in Neural Systems".
Professor Goodhill's lab uses theoretical, computational and experimental techniques to investigate how biological nervous systems become wired up during development. Current work is primarily focused on how growing axons find their targets by detecting molecular gradients, and how topographic maps form in the zebrafish optic tectum and the mammalian visual cortex. PhD and Honours projects are available in all of these areas.
- Frank Sengpiel, University of Cardiff
- Linda Richards, University of Queensland
- Michael Ibbotson, ANU
- Peter Dayan, University College London
- Ethan Scott (UQ)
Forbes, E.M., Thompson, A.W., Yuan, J, & Goodhill, G.J. (2012). Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance. Neuron, 74, 490-503. PDF SI
Mortimer D, Pujic Z, Vaughan T, Thompson AW, Feldner J, Vetter I, Pujic Z, & Goodhill GJ (2010). Axon guidance by growth rate modulation. Proc. Natl. Acad. Sci. USA, 107, 5202-5207. PDF
Mortimer D, Feldner J, Vaughan T, Vetter I, Pujic Z, Rosoff WJ, Burrage K, Dayan P, Richards LJ, Goodhill GJ (2009). A Bayesian model predicts the response of axons to molecular gradients. Proc. Natl. Acad. Sci. USA, 106, 10296-10301. PDF
Mortimer, D., Fothergill, T., Pujic, Z., Richards, L.J. & Goodhill, G.J. (2008). Growth Cone Chemotaxis. Trends in Neurosciences, 31, 90-98. PDF
Goodhill, G.J. (2007). Contributions of theoretical modelling to the understanding of neural map development. Neuron, 56, 301-311. PDF
Giacomantonio, C.E. & Goodhill, G.J. (2007). The effect of angioscotomas on map structure in primary visual cortex. Journal of Neuroscience, 27, 4935-4946. PDF
Xu, J., Rosoff, W.J., Urbach, J,S. & Goodhill, G.J. (2005). Adaptation is not required to explain the long-term response of axons to molecular gradients. Development, 132, 4545-4552. PDF
Rosoff, W.J., Urbach, J.S., Esrick, M., McAllister, R.G. Richards, L.J. & Goodhill, G.J. (2004). A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nature Neuroscience, 7, 678-682. PDF