In order for the human brain to function, it must be wired correctly during brain development. How this occurs is one of the fundamental questions of neuroscience.

This conference brings together international leaders in the field of normal and abnormal wiring of the cerebral cortex, and how this impacts cognitive function. A special focus will be on the development and cognitive function of the corpus callosum and the genetic basis of how callosal malformations arise, how they are diagnosed, and how these malformations impact cognition.

The corpus callosum is the largest fibre tract in the mammalian brain. It is an evolutionary innovation only found in placental mammals, with important functions in human behaviour, sensory and motor function and language. Corpus callosum malformations may be present in isolation or as part of over 64 different human congenital syndromes. Symptoms include sensory and motor deficits, language and learning difficulties and most commonly problems with social interactions.

A particular emphasis of this meeting will be to provide up-to-date information for clinical neurologists, neurosurgeons, geneticists, psychiatrists and psychologists on corpus callosum function and malformations, as well as the clinical management of patients. Sessions include development, genetics, imaging and cognitive function of cortical wiring. Participants are encouraged to submit abstracts and present posters at the meeting. A subset of abstracts will be selected for short talks in each session.

Featured speakers

Conference themes

Session 1: Development of Cortical Wiring

The development of circuits in the brain is crucial to proper function. This session will cover the cellular and molecular mechanisms required to form cortical circuits and electrophysiological properties of cortical circuits. An overview of human cortical malformations that affect cortical wiring, including agenesis of the corpus callosum, will also be discussed. 

Session 2: Genetics of Cortical Wiring Disorders

Advances in human genetics are occurring rapidly. This session will cover the latest research on identifying the causative genes of human cortical wiring disorders. Speakers will present their research using genome sequencing, single nucleotide polymorphism analysis, copy number variation, insertion and deletion analyses, mutational analysis and epigenetic regulation of gene function.

Session 3: Imaging Cortical Wiring

Neuroimaging provides a mechanism for diagnosing and potentially sub-phenotyping disorders of cortical wiring. Research using multimodal magnetic resonance imaging (T1, diffusion and functional MRI) will be highlighted as well as the computational analysis of this data in mapping cortical wiring and overall brain connectivity. Recent data demonstrating the plasticity of human cortical wiring and the development of ectopic projections in some individuals will also be discussed.

Session 4: Cognitive function and Cortical Wiring Disorders

The output of cortical wiring is the cognitive function of the brain. This session will focus on the function of the human corpus callosum and how these functions are altered in disorders of cortical wiring. The cognitive diagnosis and treatment of these individuals will also be discussed by experts in the field.

Conference program

Download the Cortical Connections 2015 program booklet.

Registrations

Registrations include access to the full two days of conference proceedings as well as morning tea, lunch and afternoon tea.

Fees

  • Full Fee Two Day Registration $375 (until 18 March 2015)
  • One Day Registration $200
  • Conference Dinner $100

Registrations for Cortical Connections 2015 are open. Click to register for Cortical Connections 2015.

Abstract submission guidelines

  • Please include title, author, affiliation, a brief description of your research and an acknowledgment of funding sources. Max 250 words. 
  • Email to qbievents@uq.edu.au by Friday 27 February.
  • Abstract submission is included in the registration (must register to submit an abstract).

Venue

Between Thursday 19th March and Friday 20th March, Cortical Connections 2015 will be held at the Queensland Brain Institute on The University of Queensland's St Lucia campus.

Address:
The Queensland Brain Institute
The University of Queensland
QBI Building (#79)
St Lucia, QLD 4072
Australia


Cortical Connections 2015 will be held in the QBI Auditorium.

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Conference organisers

Contact

For enqiuries about Cortical Connections 2015 please contact Linda Richards via: